Rome2Rio

Gainesville to San Francisco buses

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Trip Overview

The average bus between Gainesville and San Francisco takes 3d 1h and the fastest bus takes 3d. There is at least one bus per day from Gainesville to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 1h
Duration
2,978 mi
Distance
$618
Average price
Once daily
Frequency

Gainesville to San Francisco bus times

Buses run once daily between Gainesville and San Francisco. The earliest departure is at 11:30 AM in the morning, and the last departure from Gainesville is at 5:05 PM which arrives into San Francisco at 5:55 PM. All services require a transfer at Atlanta Bus Station and take an average of 3d 1h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAGreyhound USAFlixbus USA3d • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAGreyhound USAFlixbus USA3d • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAGreyhound USAFlixbus USA3d • 3 changes
  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAGreyhound USAFlixbus USA3d 3h • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAGreyhound USAFlixbus USA3d • 3 changes
  •  → 

    Arrives +3 days

    Flixbus USAGreyhound USAGreyhound USAFlixbus USA3d 3h • 3 changes

Frequently asked questions

Want to know about travelling from Gainesville to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Gainesville to San Francisco.ExpandLaunch map view
  • Distance: 2,978.2 mi
  • Duration: 3d 1h

What companies run services between Gainesville, FL, USA and San Francisco, CA, USA?

You can take a bus from Gainesville to San Francisco via Atlanta Bus Station, Dallas Bus Station, and Los Angeles Union Station in around 2d 16h.

Operators