The average bus between Garden Grove and La Mesa takes 6h 22m and the fastest bus takes 3h 59m. The bus service runs several times per day from Garden Grove to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Garden Grove and La Mesa. The earliest departure is at 9:18 AM in the morning, and the last departure from Garden Grove is at 6:58 PM which arrives into La Mesa at 6:51 AM. All services require a transfer at Santa Ana and take an average of 6h 22m. The schedules shown below are for the next available departures.



3h 59m • 3 changes



4h 22m • 3 changes
Arrives next day



11h 53m • 3 changes



3h 59m • 3 changes



4h 22m • 3 changes
Arrives next day



11h 53m • 3 changes



3h 59m • 3 changes



4h 22m • 3 changes
Arrives next day



11h 53m • 3 changes
Want to know about travelling from Garden Grove to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Garden Grove to La Mesa. However, there are services departing from Garden Grove station and arriving at La Mesa station via San Diego. The journey, including transfers, takes approximately 6h 22m.
Garden Grove to La Mesa bus services, operated by OCTA, depart from Santa Ana station.
Garden Grove to La Mesa bus services, operated by OCTA, arrive at San Diego station.
The distance between Garden Grove and La Mesa is 140.7 km. The road distance is 172 km.
Greyhound Mexico operates a bus from Santa Ana to San Diego 3 times a day. Tickets cost $18–28 and the journey takes 1h 45m.