Bus Gare de Lyon-Perrache to Florence from €71 | Tickets & Timetables

Gare de Lyon-Perrache to Florence buses

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Trip Overview

The average bus between Gare de Lyon-Perrache and Florence takes 11h 46m and the fastest bus takes 10h 5m. The bus service runs several times per day from Gare de Lyon-Perrache to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 46m
Duration: 699 km
Distance: €71
Average price: 4 times a day
Frequency

Bus via Genoa

best

Take the bus from Lyon to Genoabus N580 / ...
Take the bus from Genoa to Florence Villa Constanza Bus Stationbus 510 / ...

10h 30m

€60–103

Gare de Lyon-Perrache to Florence bus times

Buses run 4 times a day between Gare de Lyon-Perrache and Florence. The earliest departure is at 2:15 AM at night, and the last departure from Gare de Lyon-Perrache is at 8:45 PM which arrives into Florence at 8:30 AM. All services require a transfer, and take on average 11h 46m. The schedules shown below are for the next available departures.

Departing Wednesday, August 19, 2026

2:15 AM → 6:05 PM
15h 50m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change
8:45 PM → 8:30 AM
Arrives next day
11h 45m • 1 change

Departing Thursday, August 20, 2026

2:15 AM → 4:40 PM
14h 25m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change
8:45 PM → 8:30 AM
Arrives next day
11h 45m • 1 change

Departing Friday, August 21, 2026

2:15 AM → 4:40 PM
14h 25m • 1 change
9:35 AM → 7:40 PM
10h 5m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change
8:45 PM → 8:30 AM
Arrives next day
11h 45m • 1 change

Departing Saturday, August 22, 2026

2:15 AM → 4:40 PM
14h 25m • 1 change
9:35 AM → 7:40 PM
10h 5m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change
8:45 PM → 8:30 AM
Arrives next day
11h 45m • 1 change

Departing Sunday, August 23, 2026

2:15 AM → 4:40 PM
14h 25m • 1 change
9:35 AM → 7:40 PM
10h 5m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change
8:45 PM → 8:30 AM
Arrives next day
11h 45m • 1 change

Departing Monday, August 24, 2026

2:15 AM → 4:40 PM
14h 25m • 1 change
9:35 AM → 7:40 PM
10h 5m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change
8:45 PM → 8:30 AM
Arrives next day
11h 45m • 1 change

Departing Tuesday, August 25, 2026

2:15 AM → 4:40 PM
14h 25m • 1 change
9:35 AM → 7:40 PM
10h 5m • 1 change
10:50 AM → 9:00 PM
10h 10m • 1 change

Frequently asked questions

Want to know about travelling from Gare de Lyon-Perrache to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.