The average bus between Gare de Lyon and Avignon Centre takes 9h 18m and the fastest bus takes 8h 44m. The bus service runs several times per day from Gare de Lyon to Avignon Centre. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Gare de Lyon and Avignon Centre. The earliest departure is at 7:00 AM in the morning, and the last departure from Gare de Lyon is at 10:35 PM which arrives into Avignon Centre at 7:19 AM. All services require a transfer at Paris, Quai de Bercy (Bercy Seine) and take an average of 9h 18m. The schedules shown below are for the next available departures.
Arrives next day

9h 5m • 1 change
Arrives next day

8h 44m • 1 change

9h 48m • 1 change
Arrives next day

9h 5m • 1 change
Arrives next day

8h 44m • 1 change

9h 48m • 1 change
Arrives next day

9h 5m • 1 change
Arrives next day

8h 44m • 1 change
Want to know about travelling from Gare de Lyon to Avignon Centre? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Gare de Lyon to Avignon Centre. However, there are services departing from Gare de Lyon station and arriving at Avignon Centre station via Avignon. The journey, including transfers, takes approximately 9h 18m.
Gare de Lyon to Avignon Centre bus services, operated by FlixBus, depart from Paris, Quai de Bercy (Bercy Seine) station.
Gare de Lyon to Avignon Centre bus services, operated by FlixBus, arrive at Avignon station.
The distance between Gare de Lyon and Avignon Centre is 576.1 km. The road distance is 696 km.
FlixBus operates a bus from Paris, Quai de Bercy (Bercy Seine) to Avignon twice daily. Tickets cost €60–110 and the journey takes 8h 15m.