The average bus between Gare de Strasbourg and Lyon takes 7h 39m and the fastest bus takes 6h 34m. The bus service runs several times per day from Gare de Strasbourg to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Gare de Strasbourg and Lyon. The earliest departure is at 12:34 AM at night, and the last departure from Gare de Strasbourg is at 9:54 PM which arrives into Lyon at 5:10 AM. All services require a transfer at Etoile Bourse and take an average of 7h 39m. The schedules shown below are for the next available departures.

8h 45m • 1 change

7h 56m • 1 change

6h 34m • 1 change
Arrives next day

7h 29m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change

7h 41m • 1 change

7h 26m • 1 change

9h 1m • 1 change

7h 52m • 1 change

7h 41m • 1 change

7h 26m • 1 change

9h 1m • 1 change

7h 52m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change

7h 41m • 1 change

7h 36m • 1 change

8h 45m • 1 change

7h 56m • 1 change
Want to know about travelling from Gare de Strasbourg to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Gare de Strasbourg to Lyon. However, there are services departing from Gare de Strasbourg station and arriving at Lyon station via Lyon. The journey, including transfers, takes approximately 7h 39m.
Gare de Strasbourg to Lyon bus services, operated by CTS - Compagnie des Transports Strasbourgeois, depart from Strasbourg station.
Gare de Strasbourg to Lyon bus services, operated by CTS - Compagnie des Transports Strasbourgeois, arrive at Lyon station.
The distance between Gare de Strasbourg and Lyon is 383.5 km. The road distance is 497 km.
FlixBus operates a bus from Strasbourg to Lyon every 4 hours. Tickets cost €40–70 and the journey takes 6h 45m. BlaBlaCar Bus also services this route 5 times a day.