The average bus between Gare de Strasbourg and Lyon takes 7h 27m and the fastest bus takes 6h 35m. The bus service runs several times per day from Gare de Strasbourg to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Gare de Strasbourg and Lyon. The earliest departure is at 12:34 AM at night, and the last departure from Gare de Strasbourg is at 9:54 PM which arrives into Lyon at 5:10 AM. All services require a transfer at Etoile Bourse and take an average of 7h 27m. The schedules shown below are for the next available departures.

7h 26m • 1 change
9h 1m • 1 change
8h • 1 change
6h 45m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 change
6h 35m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 changeArrives next day

7h 5m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 change
6h 35m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 56m • 1 change
6h 35m • 1 change
7h 41m • 1 change
7h 36m • 1 change
7h 50m • 1 change
6h 36m • 1 changeWant to know about travelling from Gare de Strasbourg to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Gare de Strasbourg to Lyon. However, there are services departing from Strasbourg station and arriving at Lyon station via Lyon station. The journey, including transfers, takes approximately 7h 27m.
Gare de Strasbourg to Lyon bus services, operated by FlixBus, depart from Strasbourg station.
Gare de Strasbourg to Lyon bus services, operated by FlixBus, arrive at Lyon station.
The distance between Gare de Strasbourg and Lyon is 383.5 km. The road distance is 457 km.
FlixBus operates a bus from Strasbourg to Lyon 4 times a day. Tickets cost €40–65 and the journey takes 6h 45m. BlaBlaCar Bus also services this route 4 times a day.