The average bus between Genoa and Domodossola takes 5h 11m and the fastest bus takes 4h 10m. The bus service runs several times per day from Genoa to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Genoa and Domodossola. The earliest departure is at 2:50 AM at night, and the last departure from Genoa is at 3:00 PM which arrives into Domodossola at 7:10 PM. All services require a transfer at Milan and take an average of 5h 11m. The schedules shown below are for the next available departures.

5h 50m • 1 change
6h 20m • 1 change
4h 20m • 1 change
4h 10m • 1 change
5h 50m • 1 change
6h 20m • 1 change
4h 20m • 1 change
4h 10m • 1 change
5h 50m • 1 change
6h 20m • 1 change
4h 20m • 1 change
4h 10m • 1 changeWant to know about travelling from Genoa to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Genoa to Domodossola. However, there are services departing from Genoa station and arriving at Domodossola station via Milan. The journey, including transfers, takes approximately 5h 11m.
Genoa to Domodossola bus services, operated by FlixBus, depart from Genoa station.
Genoa to Domodossola bus services, operated by FlixBus, arrive at Domodossola - Stazione Ferroviaria station.
The distance between Genoa and Domodossola is 197 km. The road distance is 261 km.
You can take a bus from Genoa to Domodossola - Stazione Ferroviaria via Milan and Aeroporto Malpensa - Terminal 1 in around 5h.