The average bus between Gießen and Mainz takes 6h 13m and the fastest bus takes 4h. The bus service runs several times per day from Gießen to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Gießen and Mainz. The earliest departure is at 3:30 PM in the afternoon, and the last departure from Gießen is at 7:30 PM which arrives into Mainz at 8:15 AM. All services require a transfer, and take on average 6h 13m. The schedules shown below are for the next available departures.

2h • 1 change

2h 20m • 1 change
Arrives next day

12h 45m • 1 change

2h • 1 change

4h 45m • 1 change
Arrives next day

12h 45m • 1 change

2h • 1 change

2h 20m • 1 change
Arrives next day

12h 45m • 1 change

2h • 1 change

4h 45m • 1 change
Arrives next day

12h 45m • 1 change

2h • 1 change

4h 45m • 1 change
Arrives next day

12h 45m • 1 change
Want to know about travelling from Gießen to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Gießen to Mainz. However, there are services departing from Gießen station and arriving at Mainz station via Frankfurt central train station station. The journey, including transfers, takes approximately 6h 13m.
Gießen to Mainz bus services, operated by FlixBus, depart from Gießen station.
Gießen to Mainz bus services, operated by FlixBus, arrive at Mainz central train station.
Book your Gießen to Mainz bus tickets online with FlixBus.
The distance between Gießen and Mainz is 72.7 km. The road distance is 100 km.
You can take a bus from Gießen to Mainz central train station via Frankfurt central train station in around 2h 40m.