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Grand Central Terminal to St. Louis buses

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Trip Overview

The average bus between Grand Central Terminal and St. Louis takes 23h 35m and the fastest bus takes 22h 25m. The bus service runs several times per day from Grand Central Terminal to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 35m
Duration
1,048 mi
Distance
$220
Average price
3 times a day
Frequency

Grand Central Terminal to St. Louis bus times

Buses run 3 times a day between Grand Central Terminal and St. Louis. The earliest departure is at 1:25 AM at night, and the last departure from Grand Central Terminal is at 3:10 PM which arrives into St. Louis at 3:10 PM. All services run direct with no transfers required, and take on average 23h 35m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    bus bus 25h • Direct

Departing Thursday, November 12, 2026

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    bus bus 22h 25m • Direct
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    Arrives next day

    bus bus 23h 20m • Direct
  •  → 

    Arrives next day

    bus bus 25h • Direct

Departing Friday, November 13, 2026

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    bus bus 22h 25m • Direct
  •  → 

    Arrives next day

    bus bus 23h 20m • Direct
  •  → 

    Arrives next day

    bus bus 25h • Direct

Departing Saturday, November 14, 2026

  •  → 

    bus bus 22h 25m • Direct
  •  → 

    Arrives next day

    bus bus 23h 20m • Direct
  •  → 

    Arrives next day

    bus bus 25h • Direct

Departing Sunday, November 15, 2026

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    bus bus 22h 25m • Direct
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    Arrives next day

    bus bus 23h 20m • Direct
  •  → 

    Arrives next day

    bus bus 25h • Direct

Departing Monday, November 16, 2026

  •  → 

    bus bus 22h 25m • Direct
  •  → 

    Arrives next day

    bus bus 23h 20m • Direct
  •  → 

    Arrives next day

    bus bus 25h • Direct

Departing Tuesday, November 17, 2026

  •  → 

    bus bus 22h 25m • Direct
  •  → 

    Arrives next day

    bus bus 23h 20m • Direct
  •  → 

    Arrives next day

    bus bus 25h • Direct

Frequently asked questions

Want to know about travelling from Grand Central Terminal to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Grand Central Terminal to St. Louis.ExpandLaunch map view
  • Distance: 1,048.5 mi
  • Duration: 23h 35m

What companies run services between Grand Central Terminal, NY, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Port Authority Bus Terminal to St Louis Bus Station 3 times a day. Tickets cost $190–280 and the journey takes 22h 25m.

Operators