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Green Cove Springs to Florida Keys buses

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Trip Overview

The average bus between Green Cove Springs and Florida Keys takes 2d 10h and the fastest bus takes 44h 33m. The bus runs, on average, 4 times per week from Green Cove Springs to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 10h
Duration
556 mi
Distance
$99
Average price
4 times a week
Frequency

Green Cove Springs to Florida Keys bus times

Buses run 4 times a week between Green Cove Springs and Florida Keys. The earliest departure is at 12:42 PM in the afternoon, and the last departure from Green Cove Springs is at 3:42 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Keystone Heights Senior Center and take an average of 2d 10h. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

  •  → 

    Arrives +2 days

    Jacksonville TransportJacksonville TransportFlixbus USAGreyhound USAKey West Transit47h 33m • 4 changes
  •  → 

    Arrives +4 days

    Jacksonville TransportJacksonville TransportFlixbus USAGreyhound USAKey West Transit3d 20h • 4 changes

Departing Monday, October 19, 2026

  •  → 

    Arrives +2 days

    Jacksonville TransportJacksonville TransportFlixbus USAGreyhound USAKey West Transit44h 33m • 4 changes

Departing Tuesday, October 20, 2026

  •  → 

    Arrives +2 days

    Jacksonville TransportJacksonville TransportFlixbus USAGreyhound USAKey West Transit47h 33m • 4 changes

Frequently asked questions

Want to know about travelling from Green Cove Springs to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Green Cove Springs to Florida Keys.ExpandLaunch map view
  • Distance: 556.4 mi
  • Duration: 2d 10h

What companies run services between Green Cove Springs, FL, USA and Florida Keys, FL, USA?

You can take a bus from Clay County Senior Services to Florida Keys via Keystone Heights Senior Center, Gainesville, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 18h 8m.

Operators