The average bus between Grenoble and Karlsruhe takes 11h 54m and the fastest bus takes 9h 50m. The bus service runs several times per day from Grenoble to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Grenoble and Karlsruhe. The earliest departure is at 4:25 AM at night, and the last departure from Grenoble is at 11:30 PM which arrives into Karlsruhe at 10:50 AM. All services require a transfer, and take on average 11h 54m. The schedules shown below are for the next available departures.

12h 45m • 1 changeArrives next day

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11h 5m • 1 changeArrives next day

11h 25m • 1 change
12h 45m • 1 changeArrives next day

10h 50m • 1 changeArrives next day

9h 50m • 1 changeArrives next day

11h 25m • 1 change
12h 45m • 1 changeArrives next day

10h 50m • 1 changeArrives next day

9h 50m • 1 changeArrives next day

11h 25m • 1 change
12h 35m • 1 changeArrives next day

10h 50m • 1 changeArrives next day

9h 50m • 1 changeArrives next day

11h 25m • 1 changeWant to know about travelling from Grenoble to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Grenoble to Karlsruhe. However, there are services departing from Grenoble station and arriving at Karlsruhe station via Lyon. The journey, including transfers, takes approximately 11h 54m.
Grenoble to Karlsruhe bus services, operated by BlaBlaCar Bus, depart from Grenoble station.
Grenoble to Karlsruhe bus services, operated by BlaBlaCar Bus, arrive at Karlsruhe central train station.
Book your Grenoble to Karlsruhe bus tickets online with BlaBlaCar Bus and FlixBus.
The distance between Grenoble and Karlsruhe is 472 km. The road distance is 677 km.
You can take a bus from Grenoble to Karlsruhe central train station via Lyon in around 10h 15m.