The average bus between Grenoble and Vesoul takes 9h 19m and the fastest bus takes 7h 46m. The bus service runs several times per day from Grenoble to Vesoul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Grenoble and Vesoul. The earliest departure is at 12:45 AM at night, and the last departure from Grenoble is at 10:30 PM which arrives into Vesoul at 7:21 AM. All services require a transfer at Lyon and take an average of 9h 19m. The schedules shown below are for the next available departures.


11h 5m • 2 changes


7h 46m • 2 changes
Arrives next day


8h 51m • 2 changes


11h 5m • 2 changes


7h 46m • 2 changes
Arrives next day


8h 51m • 2 changes
Want to know about travelling from Grenoble to Vesoul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Grenoble to Vesoul. However, there are services departing from Grenoble station and arriving at Vesoul station via Lyon - Gerland Bus Station station. The journey, including transfers, takes approximately 9h 19m.
Grenoble to Vesoul bus services, operated by FlixBus, depart from Grenoble - Bus Station.
Grenoble to Vesoul bus services, operated by FlixBus, arrive at Pôle Multimodal station.
The distance between Grenoble and Vesoul is 274.1 km. The road distance is 376 km.
You can take a bus from Grenoble - Bus Station to Pôle Multimodal via Lyon and PEM Viotte in around 7h 5m.