The average bus between Groningen and Brussels takes 5h 57m and the fastest bus takes 5h 30m. The bus service runs several times per day from Groningen to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Groningen and Brussels. The earliest departure is at 1:00 AM at night, and the last departure from Groningen is at 5:55 PM which arrives into Brussels at 12:30 AM. All services require a transfer, and take on average 5h 57m. The schedules shown below are for the next available departures.

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5h 30m • 1 changeWant to know about travelling from Groningen to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Groningen to Brussels. However, there are services departing from Groningen station and arriving at Brussels station via Amsterdam Sloterdijk. The journey, including transfers, takes approximately 5h 57m.
Groningen to Brussels bus services, operated by FlixBus, depart from Groningen central station.
Groningen to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Book your Groningen to Brussels bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Groningen and Brussels is 303.9 km. The road distance is 387 km.
You can take a bus from Groningen central station to Brussels-North train station via Amsterdam Sloterdijk in around 5h 28m.