The average bus between Guadalajara and Cholula takes 10h 23m and the fastest bus takes 9h 40m. The bus service runs several times per day from Guadalajara to Cholula. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Guadalajara and Cholula. The earliest departure is at 1:00 AM at night, and the last departure from Guadalajara is at 11:59 PM which arrives into Cholula at 9:45 AM. All services require a transfer at México D.F., Central De Autobuses Del Norte and take an average of 10h 23m. The schedules shown below are for the next available departures.


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11h • 2 changesWant to know about travelling from Guadalajara to Cholula? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guadalajara to Cholula. However, there are services departing from Nueva Central Camionera de Guadalajara Mod 1 station and arriving at Puebla station via Terminal Central de Autobuses del Norte station. The journey, including transfers, takes approximately 10h 23m.
Guadalajara to Cholula bus services, operated by Primera Plus, depart from Nueva Central Camionera de Guadalajara Mod 1 station.
Guadalajara to Cholula bus services, operated by Flixbus USA, arrive at Puebla station.
The distance between Guadalajara and Cholula is 562.7 km. The road distance is 664 km.
You can take a bus from Nueva Central Camionera de Guadalajara Mod 1 to Puebla via México D.F., Central De Autobuses Del Norte, Poniente 112, Norte y Aldama, and Mexico City Degollado in around 10h 48m.