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Guadalajara to Santa Ana buses

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Trip Overview

The bus between Guadalajara and Santa Ana takes 34h. There is at least one bus per day from Guadalajara to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h
Duration
1,541 mi
Distance
$191
Average price
Once daily
Frequency

Guadalajara to Santa Ana bus times

Buses run once daily between Guadalajara and Santa Ana. The earliest departure is at 6:27 PM in the evening, and the last departure from Guadalajara is at 6:29 PM which arrives into Santa Ana at 2:30 AM. All services require a transfer at Lateral Periferico and take an average of 34h. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h • 1 change

Departing Thursday, November 5, 2026

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    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h • 1 change

Departing Sunday, November 8, 2026

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    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h 2m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Mi Transporte EléctricoACN Autobuses34h • 1 change

Frequently asked questions

Want to know about travelling from Guadalajara to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guadalajara to Santa Ana.ExpandLaunch map view
  • Distance: 1,541.2 mi
  • Duration: 34h

What companies run services between Guadalajara, Mexico and Santa Ana, CA, USA?

ACN Autobuses operates a bus from Guadalajara to Santa Ana once daily. Tickets cost $80–190 and the journey takes 32h 35m.

Operators