The average bus between Guadalajara and Tlaxcala takes 9h 47m and the fastest bus takes 9h 10m. The bus service runs several times per day from Guadalajara to Tlaxcala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Guadalajara and Tlaxcala. The earliest departure is at 1:00 AM at night, and the last departure from Guadalajara is at 11:59 PM which arrives into Tlaxcala at 9:40 AM. All services require a transfer at México D.F., Central De Autobuses Del Norte and take an average of 9h 47m. The schedules shown below are for the next available departures.



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Want to know about travelling from Guadalajara to Tlaxcala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guadalajara to Tlaxcala. However, there are services departing from Guadalajara station and arriving at Tlaxcala station via Terminal Central de Autobuses del Norte. The journey, including transfers, takes approximately 9h 47m.
Guadalajara to Tlaxcala bus services, operated by Primera Plus, depart from Nueva Central Camionera de Guadalajara Mod 1 station.
Guadalajara to Tlaxcala bus services, operated by Primera Plus, arrive at Tlaxcala station.
The distance between Guadalajara and Tlaxcala is 562.8 km. The road distance is 650 km.
You can take a bus from Nueva Central Camionera de Guadalajara Mod 1 to Tlaxcala via México D.F., Central De Autobuses Del Norte, Av. 100 Metros - Frente a Metro Central Camionera, Teatro Blanquita, San Lázaro, and México TAPO in around 9h 14m.