The average bus between Guadalajara and Tlaxco takes 11h 45m and the fastest bus takes 11h 25m. The bus service runs several times per day from Guadalajara to Tlaxco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Guadalajara and Tlaxco. The earliest departure is at 12:30 AM at night, and the last departure from Guadalajara is at 11:40 PM which arrives into Tlaxco at 11:05 AM. All services require a transfer, and take on average 11h 45m. The schedules shown below are for the next available departures.

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11h 35m • 1 change

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Want to know about travelling from Guadalajara to Tlaxco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guadalajara to Tlaxco. However, there are services departing from Guadalajara station and arriving at Tlaxco station via Terminal Central de Autobuses del Norte. The journey, including transfers, takes approximately 11h 45m.
Guadalajara to Tlaxco bus services, operated by Primera Plus, depart from Nueva Central Camionera de Guadalajara Mod 1 station.
Guadalajara to Tlaxco bus services, operated by Primera Plus, arrive at Tlaxco station.
The distance between Guadalajara and Tlaxco is 562.6 km. The road distance is 698 km.
You can take a bus from Nueva Central Camionera de Guadalajara Mod 1 to Tlaxco via Terminal Central de Autobuses del Norte in around 12h.