The average bus between Guanajuato and Cancún takes 33h 50m and the fastest bus takes 32h 30m. The bus service runs several times per day from Guanajuato to Cancún. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Guanajuato and Cancún. The earliest departure is at 8:30 AM in the morning, and the last departure from Guanajuato is at 3:00 PM which arrives into Cancún at 12:30 AM. All services require a transfer, and take on average 33h 50m. The schedules shown below are for the next available departures.
Arrives next day

35h 10m • 1 change
Arrives next day

35h 50m • 1 change
Arrives +2 days

33h 30m • 1 change
Arrives next day

35h 10m • 1 change
Arrives next day

35h 50m • 1 change
Arrives +2 days

33h 30m • 1 change
Arrives next day

35h 10m • 1 change
Arrives next day

35h 50m • 1 change
Arrives +2 days

33h 30m • 1 change
Arrives next day

35h 10m • 1 change
Arrives next day

35h 50m • 1 change
Arrives +2 days

33h 30m • 1 change
Want to know about travelling from Guanajuato to Cancún? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guanajuato to Cancún. However, there are services departing from Guanajuato station and arriving at Cancún station via Terminal Central de Autobuses del Norte. The journey, including transfers, takes approximately 33h 50m.
Guanajuato to Cancún bus services, operated by Primera Plus, depart from Guanajuato station.
Guanajuato to Cancún bus services, operated by Primera Plus, arrive at Terminal de Autobuses ADO Cancún station.
Book your Guanajuato to Cancún bus tickets online with Primera Plus, ADO and ETN Turistar.
The distance between Guanajuato and Cancún is 1,494.8 km. The road distance is 1,966 km.
You can take a bus from Guanajuato to Terminal de Autobuses ADO Cancún via Terminal Central de Autobuses del Norte in around 33h 55m.