The average bus between Guanajuato and Cdmx takes 5h 21m and the fastest bus takes 5h 10m. The bus service runs several times per day from Guanajuato to Cdmx. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Guanajuato and Cdmx. The earliest departure is at 12:45 AM at night, and the last departure from Guanajuato is at 11:59 PM which arrives into Cdmx at 5:44 AM. All services require a transfer at México D.F., Central De Autobuses Del Norte and take an average of 5h 21m. The schedules shown below are for the next available departures.

5h 12m • 1 change

5h 45m • 1 change

5h 12m • 1 change

5h 12m • 1 change

5h 12m • 1 change

5h 11m • 1 change

5h 47m • 1 change

5h 12m • 1 change

5h 12m • 1 change

5h 11m • 1 change

5h 47m • 1 change

5h 12m • 1 change

5h 12m • 1 change

5h 11m • 1 change

5h 47m • 1 change

5h 12m • 1 change

5h 12m • 1 change

5h 11m • 1 change

5h 47m • 1 change

5h 12m • 1 change
Want to know about travelling from Guanajuato to Cdmx? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guanajuato to Cdmx. However, there are services departing from Guanajuato station and arriving at Cdmx station via Terminal Central de Autobuses del Norte. The journey, including transfers, takes approximately 5h 21m.
Guanajuato to Cdmx bus services, operated by Primera Plus, depart from Guanajuato station.
Guanajuato to Cdmx bus services, operated by Primera Plus, arrive at Terminal Central de Autobuses del Norte station.
Book your Guanajuato to Cdmx bus tickets online with Primera Plus, Corredores Concesionados CDMX and ETN Turistar.
The distance between Guanajuato and Cdmx is 281.5 km. The road distance is 346 km.
Primera Plus operates a bus from Guanajuato to Terminal Central de Autobuses del Norte every 4 hours. Tickets cost $850–1,200 and the journey takes 4h 45m. ETN Turistar also services this route 4 times a day.