- Distance: 156.7 km
- Duration: 3h 40m
The average bus between Guatemala City and Santa Ana takes 3h 40m and the fastest bus takes 3h 25m. The bus service runs several times per day from Guatemala City to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Guatemala City and Santa Ana. The earliest departure is at 6:05 AM in the morning, and the last departure from Guatemala City is at 1:35 PM which arrives into Santa Ana at 5:00 PM. All services run direct with no transfers required, and take on average 3h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Guatemala City to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Guatemala City station and arriving at Santa Ana station. Services depart twice daily, and operate 3 times a day. The journey takes approximately 3h 40m.
Guatemala City to Santa Ana bus services, operated by GuateGo, depart from Guatemala City station.
Guatemala City to Santa Ana bus services, operated by GuateGo, arrive at Santa Ana station.
Book your Guatemala City to Santa Ana bus tickets online with GuateGo.
The distance between Guatemala City and Santa Ana is 125.4 km. The road distance is 157 km.
Pullmantur operates a bus from Guatemala City to Santa Ana every 4 hours. Tickets cost $29–55 and the journey takes 5h. Two other operators also service this route.
