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Guelph to Louisville buses

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Trip Overview

The average bus between Guelph and Louisville takes 34h 15m and the fastest bus takes 32h 28m. The bus runs, on average, 2 times per week from Guelph to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h 15m
Duration
607 mi
Distance
$124
Average price
Twice a week
Frequency

Guelph to Louisville bus times

Buses run twice a week between Guelph and Louisville. The earliest departure is at 6:52 PM in the evening, and the last departure from Guelph is at 10:27 PM which arrives into Louisville at 6:55 AM. All services require a transfer at Victoria / Bingemans Centre Dr. and take an average of 34h 15m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    GO TransitGO TransitFlixbus USABarons BusAmtrak Thruway36h 3m • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    GO TransitGrand River TransitFlixbus USABarons BusAmtrak Thruway32h 28m • 4 changes

Frequently asked questions

Want to know about travelling from Guelph to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guelph to Louisville.ExpandLaunch map view
  • Distance: 606.9 mi
  • Duration: 34h 15m

What companies run services between Guelph, ON, Canada and Louisville, KY, USA?

You can take a bus from Guelph Central GO Bus to Louisville, KY via Victoria / Bingemans Centre Dr., Kitchener, Detroit, and Indianapolis Union Station in around 16h 24m.

Operators