Rome2Rio

Guelph to San Diego buses

Find Transport to San Diego

View schedule

Trip Overview

The bus between Guelph and San Diego takes 4d 22h. The bus runs, on average, 2 times per week from Guelph to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4d 22h
Duration
2,942 mi
Distance
Twice a week
Frequency

Guelph to San Diego bus times

Buses run twice a week between Guelph and San Diego. The earliest departure is at 9:45 AM in the morning, and the last departure from Guelph is at 9:45 AM which arrives into San Diego at 5:35 AM. All services require a transfer at Toronto and take an average of 4d 22h. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

  •  → 

    Arrives +5 days

    Flixbus USAFlixbus USACOTAGreyhound USAGreyhound USAAmtrak4d 22h • 5 changes

Departing Monday, October 19, 2026

  •  → 

    Arrives +5 days

    Flixbus USAFlixbus USACOTAGreyhound USAGreyhound USAAmtrak4d 22h • 5 changes

Frequently asked questions

Want to know about travelling from Guelph to San Diego? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guelph to San Diego.ExpandLaunch map view
  • Distance: 2,942 mi
  • Duration: 4d 22h

What companies run services between Guelph, ON, Canada and San Diego, CA, USA?

You can take a bus from Guelph to San Diego via Toronto, Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 20h.

Operators