Rome2Rio

Guelph to San Francisco buses

Find Transport to San Francisco

View schedule

Trip Overview

The bus between Guelph and San Francisco takes 5d 1h. The bus runs, on average, 2 times per week from Guelph to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5d 1h
Duration
3,207 mi
Distance
$679
Average price
Twice a week
Frequency

Guelph to San Francisco bus times

Buses run twice a week between Guelph and San Francisco. The service departs Guelph at 9:45 AM in the morning, which arrives into San Francisco at 08:30:00. All services require a transfer at Toronto and take an average of 5d 1h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +5 days

    Flixbus USAFlixbus USACOTAGreyhound USAGreyhound USAFlixbus USA5d 1h • 5 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +5 days

    Flixbus USAFlixbus USACOTAGreyhound USAGreyhound USAFlixbus USA5d 1h • 5 changes

Frequently asked questions

Want to know about travelling from Guelph to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guelph to San Francisco.ExpandLaunch map view
  • Distance: 3,206.7 mi
  • Duration: 5d 1h

What companies run services between Guelph, ON, Canada and San Francisco, CA, USA?

You can take a bus from Guelph to San Francisco via Toronto, Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, St Louis Bus Station, and Los Angeles Union Station in around 3d 1h.

Operators