The average bus between Guimarães and Setúbal takes 5h 10m and the fastest bus takes 5h 2m. The bus service runs several times per day from Guimarães to Setúbal. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Guimarães and Setúbal. The earliest departure is at 8:30 AM in the morning, and the last departure from Guimarães is at 5:00 PM which arrives into Setúbal at 10:07 PM. All services require a transfer, and take on average 5h 10m. The schedules shown below are for the next available departures.

5h 22m • 1 change

5h 22m • 1 change

5h 7m • 1 change

5h 7m • 1 change

5h 22m • 1 change

5h 22m • 1 change

5h 7m • 1 change

5h 7m • 1 change

5h 22m • 1 change

5h 2m • 1 change

5h 7m • 1 change

5h 7m • 1 change

5h 22m • 1 change

5h 2m • 1 change

5h 7m • 1 change

5h 7m • 1 change
Want to know about travelling from Guimarães to Setúbal? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Guimarães to Setúbal. However, there are services departing from Guimarães station and arriving at Setúbal station via Estação Rodoviária de Lisboa Oriente. The journey, including transfers, takes approximately 5h 10m.
Guimarães to Setúbal bus services, operated by Rede Expressos, depart from Central de Camionagem de Guimarães station.
Guimarães to Setúbal bus services, operated by Rede Expressos, arrive at Avenida Dom João II station.
Book your Guimarães to Setúbal bus tickets online with Rede Expressos and Carris Metropolitana.
The distance between Guimarães and Setúbal is 328.6 km. The road distance is 401 km.
You can take a bus from Central de Camionagem de Guimarães to Avenida Dom João II via Estação Rodoviária de Lisboa Oriente in around 5h 6m.