The average bus between Harlem and Boston takes 5h 37m and the fastest bus takes 4h 56m. There is a bus service every few hours from Harlem to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Harlem and Boston. The earliest departure is at 12:38 AM at night, and the last departure from Harlem is at 11:10 PM which arrives into Boston at 4:40 AM. All services require a transfer at 42 St-Port Authority Bus Terminal and take an average of 5h 37m. The schedules shown below are for the next available departures.

5h 17m • 1 change
6h 1m • 1 change
5h 8m • 1 change
4h 56m • 1 change
5h 27m • 1 change
6h 2m • 1 change
5h 17m • 1 change
5h 4m • 1 change
5h 27m • 1 change
6h 2m • 1 change
5h 17m • 1 change
5h 35m • 1 change
5h 27m • 1 change
6h 2m • 1 change
5h 17m • 1 change
5h 50m • 1 changeWant to know about travelling from Harlem to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harlem to Boston. However, there are services departing from Harlem station and arriving at Boston station via Boston. The journey, including transfers, takes approximately 5h 37m.
Harlem to Boston bus services, operated by MTA Bus Company, depart from New York station.
Harlem to Boston bus services, operated by MTA Bus Company, arrive at Boston station.
The distance between Harlem and Boston is 295.5 km. The road distance is 350 km.
Peter Pan Bus Lines operates a bus from New York to Boston hourly. Tickets cost $45–95 and the journey takes 4h 35m.