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Harlem to Hyannis buses

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Trip Overview

The average bus between Harlem and Hyannis takes 7h 21m and the fastest bus takes 6h 55m. The bus service runs several times per day from Harlem to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 21m
Duration
279 mi
Distance
$74
Average price
4 times a day
Frequency

Harlem to Hyannis bus times

Buses run 4 times a day between Harlem and Hyannis. The earliest departure is at 1:05 AM at night, and the last departure from Harlem is at 6:25 PM which arrives into Hyannis at 1:35 AM. All services require a transfer at Boston and take an average of 7h 21m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

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    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton8h 15m • 1 change

Departing Saturday, October 31, 2026

  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton8h 15m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    Greyhound USAPlymouth & Brockton8h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton8h 15m • 1 change

Departing Monday, November 2, 2026

  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton8h 15m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton8h 15m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton8h 15m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton6h 55m • 1 change
  •  → 

    Greyhound USAPlymouth & Brockton7h 10m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPlymouth & Brockton7h 10m • 1 change

Frequently asked questions

Want to know about travelling from Harlem to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Harlem to Hyannis.ExpandLaunch map view
  • Distance: 278.9 mi
  • Duration: 7h 21m

What companies run services between Harlem, NY, USA and Hyannis, MA, USA?

You can take a bus from New York to Hyannis Transportation Center via Boston and Boston South Buses in around 6h 47m.

Operators