The average bus between Harpenden and Southampton takes 5h 10m and the fastest bus takes 3h 35m. The bus service runs several times per day from Harpenden to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Harpenden and Southampton. The earliest departure is at 6:28 AM in the morning, and the last departure from Harpenden is at 10:06 PM which arrives into Southampton at 9:50 AM. All services require a transfer at Luton Station Interchange and take an average of 5h 10m. The schedules shown below are for the next available departures.


4h 52m • 2 changes


4h 5m • 2 changes


3h 38m • 2 changes


4h 46m • 2 changes


4h 52m • 2 changes


4h 5m • 2 changes


3h 38m • 2 changes


4h 46m • 2 changes


4h 52m • 2 changes


4h 5m • 2 changes


4h 18m • 2 changes


5h 56m • 2 changes


4h 14m • 2 changes


5h 12m • 2 changes


5h 37m • 2 changes


6h 13m • 2 changes


4h 52m • 2 changes


4h 5m • 2 changes


4h 8m • 2 changes


5h 11m • 2 changes
Want to know about travelling from Harpenden to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harpenden to Southampton. However, there are services departing from Harpenden station and arriving at Southampton station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 5h 10m.
Harpenden to Southampton bus services, operated by Uno, depart from Luton Station Interchange.
Harpenden to Southampton bus services, operated by Uno, arrive at Coach Station.
The distance between Harpenden and Southampton is 124.9 km. The road distance is 178 km.
You can take a bus from Old Cock Inn to Coach Station via Luton Station Interchange and Heathrow Central Bus Station in around 4h 7m.