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Harrisburg, Pa to Indianapolis buses

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Trip Overview

The average bus between Harrisburg, Pa and Indianapolis takes 13h 10m and the fastest bus takes 12h 20m. The bus service runs several times per day from Harrisburg, Pa to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 10m
Duration
562 mi
Distance
$120
Average price
3 times a day
Frequency

Harrisburg, Pa to Indianapolis bus times

Buses run 3 times a day between Harrisburg, Pa and Indianapolis. The earliest departure is at 2:30 AM at night, and the last departure from Harrisburg, Pa is at 7:50 PM which arrives into Indianapolis at 9:20 AM. All services run direct with no transfers required, and take on average 13h 10m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    Arrives next day

    bus bus 13h 30m • Direct

Departing Friday, November 6, 2026

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    Arrives next day

    bus bus 12h 20m • Direct
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    Arrives next day

    bus bus 13h 25m • Direct
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    Arrives next day

    bus bus 13h 30m • Direct

Departing Saturday, November 7, 2026

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    bus bus 13h 30m • Direct
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    Arrives next day

    bus bus 12h 20m • Direct
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    Arrives next day

    bus bus 13h 25m • Direct
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    Arrives next day

    bus bus 13h 30m • Direct

Departing Sunday, November 8, 2026

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    bus bus 13h 30m • Direct
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    Arrives next day

    bus bus 12h 20m • Direct
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    Arrives next day

    bus bus 13h 25m • Direct
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    Arrives next day

    bus bus 13h 30m • Direct

Departing Monday, November 9, 2026

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    bus bus 13h 30m • Direct
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    Arrives next day

    bus bus 12h 20m • Direct
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    Arrives next day

    bus bus 13h 25m • Direct
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    Arrives next day

    bus bus 13h 30m • Direct

Departing Tuesday, November 10, 2026

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    Arrives next day

    bus bus 13h 25m • Direct
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    Arrives next day

    bus bus 13h 30m • Direct

Departing Wednesday, November 11, 2026

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    Arrives next day

    bus bus 12h 20m • Direct
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    Arrives next day

    bus bus 13h 25m • Direct

Frequently asked questions

Want to know about travelling from Harrisburg, Pa to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Harrisburg, Pa to Indianapolis.ExpandLaunch map view
  • Distance: 561.5 mi
  • Duration: 13h 10m

What companies run services between Harrisburg, Pa, PA, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from Harrisburg Bus Station to Indianapolis Union Station 4 times a day. Tickets cost $100–160 and the journey takes 13h 25m. Flixbus USA also services this route 3 times a day.

Operators