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Harrisburg, Pa to Missouri buses

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Trip Overview

The average bus between Harrisburg, Pa and Missouri takes 28h 20m and the fastest bus takes 26h 55m. The bus service runs several times per day from Harrisburg, Pa to Missouri. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 20m
Duration
1,052 mi
Distance
$230
Average price
Twice daily
Frequency

Harrisburg, Pa to Missouri bus times

Buses run twice daily between Harrisburg, Pa and Missouri. The earliest departure is at 2:45 PM in the afternoon, and the last departure from Harrisburg, Pa is at 7:50 PM which arrives into Missouri at 9:45 PM. All services require a transfer, and take on average 28h 20m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Greyhound USAGreyhound USA26h 55m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAGreyhound USA30h • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA26h 55m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA30h • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA26h 55m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA30h • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA26h 55m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA30h • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA26h 55m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA30h • 1 change
  •  → 

    Arrives next day

    Greyhound USAGreyhound USA26h 55m • 1 change

Frequently asked questions

Want to know about travelling from Harrisburg, Pa to Missouri? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Harrisburg, Pa to Missouri.ExpandLaunch map view
  • Distance: 1,052.5 mi
  • Duration: 28h 20m

What companies run services between Harrisburg, Pa, PA, USA and Missouri, USA?

You can take a bus from Harrisburg Bus Station to Kansas City Bus Station via St Louis Bus Station in around 23h 30m.

Operators