The average bus between Harrisburg, Pa and Salem takes 14h 18m and the fastest bus takes 11h 23m. The bus service runs several times per day from Harrisburg, Pa to Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Harrisburg, Pa and Salem. The earliest departure is at 12:45 AM at night, and the last departure from Harrisburg, Pa is at 2:35 PM which arrives into Salem at 7:49 AM. All services require a transfer at New York Midtown and take an average of 14h 18m. The schedules shown below are for the next available departures.



12h 25m • 3 changes



12h 31m • 3 changes
Arrives next day



17h 14m • 3 changes



12h 25m • 3 changes



12h 31m • 3 changes
Arrives next day



20h 54m • 3 changes



12h 25m • 3 changes



12h 31m • 3 changes
Arrives next day



20h 54m • 3 changes
Want to know about travelling from Harrisburg, Pa to Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harrisburg, Pa to Salem. However, there are services departing from Harrisburg, Pa station and arriving at Salem station via New York Midtown. The journey, including transfers, takes approximately 14h 18m.
Harrisburg, Pa to Salem bus services, operated by Greyhound USA, depart from Harrisburg Bus Station.
Harrisburg, Pa to Salem bus services, operated by Greyhound USA, arrive at Boston station.
The distance between Harrisburg, Pa and Salem is 558.4 km. The road distance is 724 km.
You can take a bus from Harrisburg Bus Station to Salem via New York Midtown, Boston, South Station, Chelsea, and Chelsea in around 10h 45m.