The average bus between Hartford and Hyannis takes 4h 39m and the fastest bus takes 4h 15m. The bus service runs several times per day from Hartford to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Hartford and Hyannis. The earliest departure is at 3:45 AM at night, and the last departure from Hartford is at 8:55 PM which arrives into Hyannis at 1:35 AM. All services require a transfer at Boston and take an average of 4h 39m. The schedules shown below are for the next available departures.

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Want to know about travelling from Hartford to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hartford to Hyannis. However, there are services departing from Hartford station and arriving at Hyannis station via Boston. The journey, including transfers, takes approximately 4h 39m.
Hartford to Hyannis bus services, operated by Flixbus USA, depart from Hartford Union Station.
Hartford to Hyannis bus services, operated by Flixbus USA, arrive at Hyannis Transportation Center station.
Book your Hartford to Hyannis bus tickets online with Flixbus USA, Plymouth & Brockton and Greyhound USA.
The distance between Hartford and Hyannis is 199.8 km. The road distance is 279 km.
You can take a bus from Hartford Union Station to Hyannis Transportation Center via Boston and Boston South Buses in around 4h 21m.