The average bus between Heidelberg and Mainz Cathedral takes 2h 5m and the fastest bus takes 2h 2m. The bus service runs several times per day from Heidelberg to Mainz Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Heidelberg and Mainz Cathedral. The earliest departure is at 6:45 AM in the morning, and the last departure from Heidelberg is at 7:30 PM which arrives into Mainz Cathedral at 9:32 PM. All services require a transfer at Frankfurt and take an average of 2h 5m. The schedules shown below are for the next available departures.

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Want to know about travelling from Heidelberg to Mainz Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Heidelberg to Mainz Cathedral. However, there are services departing from Heidelberg station and arriving at Mainz Cathedral station via Frankfurt. The journey, including transfers, takes approximately 2h 5m.
Heidelberg to Mainz Cathedral bus services, operated by HEAG mobilo GmbH, depart from Heidelberg, Hilton Hotel station.
Heidelberg to Mainz Cathedral bus services, operated by HEAG mobilo GmbH, arrive at Wiesbaden-Mainz-Kastel Bahnhof station.
Book your Heidelberg to Mainz Cathedral bus tickets online with HEAG mobilo GmbH and DB Bus.
The distance between Heidelberg and Mainz Cathedral is 72.3 km. The road distance is 112 km.
You can take a bus from Heidelberg, Hilton Hotel to Mainz Cathedral via Frankfurt and Wiesbaden-Mainz-Kastel Bahnhof in around 2h 24m.