The average bus between Hemel Hempstead and Southampton takes 4h 17m and the fastest bus takes 3h 36m. The bus service runs several times per day from Hemel Hempstead to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Hemel Hempstead and Southampton. The earliest departure is at 6:50 AM in the morning, and the last departure from Hemel Hempstead is at 8:05 PM which arrives into Southampton at 1:00 AM. All services require a transfer at Watford Junction station and take an average of 4h 17m. The schedules shown below are for the next available departures.


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4h 34m • 2 changes

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4h 22m • 2 changesWant to know about travelling from Hemel Hempstead to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hemel Hempstead to Southampton. However, there are services departing from Hemel Hempstead station and arriving at Southampton station via Watford Junction station station. The journey, including transfers, takes approximately 4h 17m.
Hemel Hempstead to Southampton bus services, operated by Arriva UK, depart from Marlowes station.
Hemel Hempstead to Southampton bus services, operated by Arriva UK, arrive at Coach Station.
The distance between Hemel Hempstead and Southampton is 115.4 km. The road distance is 157 km.
You can take a bus from Marlowes to Coach Station via Watford Junction station, Heathrow Terminal 2, and Heathrow Central Bus Station in around 3h 50m.