The average bus between Hertfordshire and Manchester takes 5h 40m and the fastest bus takes 4h 23m. The bus service runs several times per day from Hertfordshire to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Hertfordshire and Manchester. The earliest departure is at 7:20 AM in the morning, and the last departure from Hertfordshire is at 9:52 PM which arrives into Manchester at 2:15 AM. All services require a transfer at Luton Station Interchange and take an average of 5h 40m. The schedules shown below are for the next available departures.


6h 11m • 2 changes

5h 5m • 2 changesArrives next day


6h 17m • 2 changesArrives next day


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4h 52m • 2 changes

5h 32m • 2 changes

6h • 2 changes

6h 2m • 2 changes

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5h 26m • 2 changes

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4h 52m • 2 changes

5h 12m • 2 changes

5h 40m • 2 changes

5h 37m • 2 changesWant to know about travelling from Hertfordshire to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hertfordshire to Manchester. However, there are services departing from Hertfordshire station and arriving at Manchester station via Manchester Central Coach Station station. The journey, including transfers, takes approximately 5h 40m.
Hertfordshire to Manchester bus services, operated by Uno, depart from Milton Keynes Coachway station.
Hertfordshire to Manchester bus services, operated by Uno, arrive at Manchester Central Coach Station.
The distance between Hertfordshire and Manchester is 227 km. The road distance is 297 km.
National Express operates a bus from Milton Keynes Coachway to Manchester Central Coach Station every 30 minutes. Tickets cost £22–40 and the journey takes 3h 55m.