Rome2Rio

Hesperia to San Francisco buses

Find Transport to San Francisco

View schedule

Trip Overview

The average bus between Hesperia and San Francisco takes 23h 14m and the fastest bus takes 20h 36m. There is at least one bus per day from Hesperia to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

23h 14m
Duration
495 mi
Distance
$134
Average price
Once daily
Frequency

Hesperia to San Francisco bus times

Buses run once daily between Hesperia and San Francisco. The earliest departure is at 10:35 AM in the morning, and the last departure from Hesperia is at 9:19 PM which arrives into San Francisco at 8:30 AM. All services require a transfer at Main St EB & Escondido Ave NS and take an average of 23h 14m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA21h 39m • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA21h 39m • 3 changes
  •  → 

    Arrives +2 days

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA35h 11m • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA21h 55m • 3 changes
  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA24h 20m • 3 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA21h 39m • 3 changes
  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA20h 36m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA21h 39m • 3 changes
  •  → 

    Arrives next day

    Victor Valley Transit AuthorityTufesaLA DOTFlixbus USA20h 36m • 3 changes

Frequently asked questions

Want to know about travelling from Hesperia to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Hesperia to San Francisco.ExpandLaunch map view
  • Distance: 494.6 mi
  • Duration: 23h 14m

What companies run services between Hesperia, CA, USA and San Francisco, CA, USA?

You can take a bus from 3rd Ave NB & Cajon St to San Francisco via Main St EB & Escondido Ave NS, Hesperia, CA, Downtown Los Angeles, Main / 7th, and Los Angeles Union Station in around 11h 30m.

Operators