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Hesperia to St. Louis buses

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Trip Overview

The average bus between Hesperia and St. Louis takes 2d 1h and the fastest bus takes 42h 14m. The bus runs, on average, 2 times per week from Hesperia to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 1h
Duration
1,926 mi
Distance
$458
Average price
Twice a week
Frequency

Hesperia to St. Louis bus times

Buses run twice a week between Hesperia and St. Louis. The service departs Hesperia at 9:19 PM at night, which arrives into St. Louis at 06:05:00. All services require a transfer at Main St EB & Escondido Ave NS and take an average of 2d 1h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +3 days

    Victor Valley Transit AuthorityTufesaFoothill TransitGreyhound USA2d 7h • 3 changes

Frequently asked questions

Want to know about travelling from Hesperia to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Hesperia to St. Louis.ExpandLaunch map view
  • Distance: 1,925.7 mi
  • Duration: 2d 1h

What companies run services between Hesperia, CA, USA and St. Louis, MO, USA?

You can take a bus from 3rd Ave NB & Cajon St to St Louis Bus Station via Main St EB & Escondido Ave NS, Hesperia, CA, 285 S East End Ave - Pomona, East End Ave and Mission Blvd E, Montclair Transit Center, and Montclair Transcenter in around 43h 17m.

Operators