The average bus between Hillingdon and Southampton takes 2h 28m and the fastest bus takes 2h 8m. There is a bus service every few hours from Hillingdon to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hillingdon and Southampton. The earliest departure is at 12:05 AM at night, and the last departure from Hillingdon is at 11:06 PM which arrives into Southampton at 1:30 AM. All services require a transfer, and take on average 2h 28m. The schedules shown below are for the next available departures.

2h 16m • 1 change

2h 16m • 1 change

2h 16m • 1 change

2h 26m • 1 change

2h 55m • 1 change

2h 39m • 1 change

2h 28m • 1 change

2h 16m • 1 change

2h 55m • 1 change

2h 39m • 1 change

2h 28m • 1 change

2h 16m • 1 change

2h 55m • 1 change

2h 39m • 1 change

2h 28m • 1 change

2h 16m • 1 change
Want to know about travelling from Hillingdon to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hillingdon to Southampton. However, there are services departing from Hillingdon station and arriving at Southampton station via Coach Station station. The journey, including transfers, takes approximately 2h 28m.
Hillingdon to Southampton bus services, operated by Metroline Travel, depart from Heathrow Central Bus Station.
Hillingdon to Southampton bus services, operated by Metroline Travel, arrive at Coach Station.
The distance between Hillingdon and Southampton is 96.3 km. The road distance is 116 km.
National Express operates a bus from Heathrow Central Bus Station to Coach Station hourly. Tickets cost £12–30 and the journey takes 1h 50m.