The average bus between Hillingdon and Southampton takes 2h 28m and the fastest bus takes 1h 58m. There is a bus service every few hours from Hillingdon to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hillingdon and Southampton. The earliest departure is at 12:05 AM at night, and the last departure from Hillingdon is at 11:35 PM which arrives into Southampton at 2:00 AM. All services require a transfer, and take on average 2h 28m. The schedules shown below are for the next available departures.

2h 45m • 1 change
2h 25m • 1 change
2h 24m • 1 change
2h 12m • 1 change
3h 4m • 1 change
2h 18m • 1 change
2h 27m • 1 change
2h 25m • 1 change
3h 4m • 1 change
2h 18m • 1 change
2h 17m • 1 change
2h 25m • 1 change
3h 4m • 1 change
1h 58m • 1 change
2h 13m • 1 change
2h 22m • 1 changeWant to know about travelling from Hillingdon to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hillingdon to Southampton. However, there are services departing from Hillingdon station and arriving at Southampton station via Coach Station station. The journey, including transfers, takes approximately 2h 28m.
Hillingdon to Southampton bus services, operated by Metroline Travel, depart from Heathrow Central Bus Station.
Hillingdon to Southampton bus services, operated by Metroline Travel, arrive at Coach Station.
The distance between Hillingdon and Southampton is 96.3 km. The road distance is 116 km.
National Express operates a bus from Heathrow Central Bus Station to Coach Station hourly. Tickets cost £11–18 and the journey takes 1h 50m.