Holyoke to Hyannis Buses

Holyoke to Hyannis buses

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Trip Overview

The average bus between Holyoke and Hyannis takes 5h 59m and the fastest bus takes 4h 35m. The bus service runs several times per day from Holyoke to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 59m
Duration: 170 mi
Distance: $36
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Springfield Union Station to Bostonbus Greyhound US0270s / ...
Take the bus from Boston to Hyannisbus Bz 0956 / ...

6h 18m

$28–62

Holyoke to Hyannis bus times

Buses run every 4 hours between Holyoke and Hyannis. The earliest departure is at 7:20 AM in the morning, and the last departure from Holyoke is at 10:30 PM which arrives into Hyannis at 9:35 AM. All services require a transfer at Union Station Bay 9 and take an average of 5h 59m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

10:30 PM → 9:35 AM
Arrives next day
11h 5m • 2 changes

Departing Saturday, October 10, 2026

7:20 AM → 12:35 PM
5h 15m • 2 changes
8:25 AM → 1:30 PM
5h 5m • 2 changes
10:55 AM → 3:30 PM
4h 35m • 2 changes
12:55 PM → 5:45 PM
4h 50m • 2 changes
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Departing Sunday, October 11, 2026

10:55 AM → 3:30 PM
4h 35m • 2 changes
12:55 PM → 5:45 PM
4h 50m • 2 changes
1:55 PM → 6:55 PM
5h • 2 changes
4:55 PM → 9:35 PM
4h 40m • 2 changes
Show more

Departing Monday, October 12, 2026

10:55 AM → 3:30 PM
4h 35m • 2 changes
12:55 PM → 5:45 PM
4h 50m • 2 changes
1:55 PM → 6:55 PM
5h • 2 changes
4:55 PM → 9:35 PM
4h 40m • 2 changes
Show more

Departing Tuesday, October 13, 2026

7:25 AM → 12:35 PM
5h 10m • 2 changes
8:25 AM → 1:30 PM
5h 5m • 2 changes
9:25 AM → 3:30 PM
6h 5m • 2 changes
12:25 PM → 5:45 PM
5h 20m • 2 changes
Show more

Departing Wednesday, October 14, 2026

7:25 AM → 12:35 PM
5h 10m • 2 changes
8:25 AM → 1:30 PM
5h 5m • 2 changes
10:55 AM → 3:30 PM
4h 35m • 2 changes
12:25 PM → 5:45 PM
5h 20m • 2 changes
Show more

Departing Thursday, October 15, 2026

7:25 AM → 12:35 PM
5h 10m • 2 changes
8:25 AM → 1:30 PM
5h 5m • 2 changes
10:55 AM → 3:30 PM
4h 35m • 2 changes
12:25 PM → 5:45 PM
5h 20m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Holyoke to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus