The average bus between Hotel Medici, Rome and Pisa takes 5h 36m and the fastest bus takes 4h 58m. The bus service runs several times per day from Hotel Medici, Rome to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Hotel Medici, Rome and Pisa. The earliest departure is at 12:36 AM at night, and the last departure from Hotel Medici, Rome is at 11:48 PM which arrives into Pisa at 5:40 AM. All services require a transfer at C.So D'italia/P.Za Fiume and take an average of 5h 36m. The schedules shown below are for the next available departures.

5h 38m • 1 change

5h 40m • 1 change

4h 58m • 1 change
Arrives next day

5h 54m • 1 change

5h 41m • 1 change

5h 41m • 1 change

5h 46m • 1 change
Arrives next day

5h 51m • 1 change

5h 43m • 1 change

5h 41m • 1 change

5h 46m • 1 change

5h 5m • 1 change

5h 43m • 1 change

5h 41m • 1 change

5h 46m • 1 change

5h 5m • 1 change

5h 43m • 1 change

5h 41m • 1 change

5h 46m • 1 change

5h 5m • 1 change
Want to know about travelling from Hotel Medici, Rome to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hotel Medici, Rome to Pisa. However, there are services departing from Hotel Medici, Rome station and arriving at Pisa station via Pisa. The journey, including transfers, takes approximately 5h 36m.
Hotel Medici, Rome to Pisa bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Hotel Medici, Rome to Pisa bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Pisa station.
The distance between Hotel Medici, Rome and Pisa is 263.2 km. The road distance is 366 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 3 times a day. Tickets cost €30–55 and the journey takes 5h 30m.