The average bus between Hotel Pisa, Rome and Florence takes 4h 3m and the fastest bus takes 3h 44m. There is a bus service every few hours from Hotel Pisa, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hotel Pisa, Rome and Florence. The earliest departure is at 6:13 AM in the morning, and the last departure from Hotel Pisa, Rome is at 10:23 PM which arrives into Florence at 2:10 AM. All services require a transfer at Conte Verde/Manzoni and take an average of 4h 3m. The schedules shown below are for the next available departures.

3h 58m • 1 change

4h 27m • 1 change

4h 3m • 1 change

4h 3m • 1 change

4h 1m • 1 change

3h 50m • 1 change

3h 52m • 1 change

3h 58m • 1 change

4h 1m • 1 change

3h 50m • 1 change

3h 52m • 1 change

3h 58m • 1 change
Want to know about travelling from Hotel Pisa, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hotel Pisa, Rome to Florence. However, there are services departing from Hotel Pisa, Rome station and arriving at Florence station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 4h 3m.
Hotel Pisa, Rome to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Hotel Pisa, Rome to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Florence Villa Constanza Bus Station.
The distance between Hotel Pisa, Rome and Florence is 233.7 km. The road distance is 280 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €23–40 and the journey takes 3h 15m. Three other operators also service this route.