The average bus between Hotel dei Mellini, Rome and Florence takes 4h 21m and the fastest bus takes 4h. There is a bus service every few hours from Hotel dei Mellini, Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hotel dei Mellini, Rome and Florence. The earliest departure is at 6:09 AM in the morning, and the last departure from Hotel dei Mellini, Rome is at 10:04 PM which arrives into Florence at 2:10 AM. All services require a transfer at Crescenzio/Orazio and take an average of 4h 21m. The schedules shown below are for the next available departures.

4h 16m • 1 change

4h 49m • 1 change
Arrives next day

4h 37m • 1 change
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4h 14m • 1 change

4h 3m • 1 change

4h 10m • 1 change

4h 1m • 1 change

4h 18m • 1 change

4h 5m • 1 change

4h 28m • 1 change

4h 15m • 1 change

4h 17m • 1 change

4h 5m • 1 change

4h 28m • 1 change

4h 15m • 1 change

4h 17m • 1 change
Want to know about travelling from Hotel dei Mellini, Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hotel dei Mellini, Rome to Florence. However, there are services departing from Hotel dei Mellini, Rome station and arriving at Florence station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 4h 21m.
Hotel dei Mellini, Rome to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Hotel dei Mellini, Rome to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Florence Villa Constanza Bus Station.
The distance between Hotel dei Mellini, Rome and Florence is 230.9 km. The road distance is 287 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €24–40 and the journey takes 3h 15m. Three other operators also service this route.