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Houston to Florence buses

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Trip Overview

The average bus between Houston and Florence takes 30h 34m and the fastest bus takes 25h 56m. The bus service runs several times per day from Houston to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

30h 34m
Duration
1,209 mi
Distance
$219
Average price
Twice daily
Frequency

Houston to Florence bus times

Buses run twice daily between Houston and Florence. The earliest departure is at 1:21 AM at night, and the last departure from Houston is at 12:13 PM which arrives into Florence at 3:10 PM. All services require a transfer at Magnolia Park Transit Center EB and take an average of 30h 34m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA25h 56m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA35h 8m • 2 changes
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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA26h 9m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA35h 7m • 2 changes
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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA26h 9m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA35h 7m • 2 changes
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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA25h 56m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA35h 8m • 2 changes
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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA25h 56m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA35h 8m • 2 changes
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    Arrives next day

    Metropolitan Transit Harris CountyGreyhound USAGreyhound USA25h 56m • 2 changes

Frequently asked questions

Want to know about travelling from Houston to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Houston to Florence.ExpandLaunch map view
  • Distance: 1,209.2 mi
  • Duration: 30h 34m

What companies run services between Houston, TX, USA and Florence, SC, USA?

You can take a vehicle from Central Station Rusk EB to Florence Bus Station via Magnolia Park Transit Center EB, Houston - Harrisburg Blvd, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 22h 50m.

Operators