The average bus between Hyannis and Boston Medical Center takes 2h 3m and the fastest bus takes 1h 53m. There is at least one bus per day from Hyannis to Boston Medical Center. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Hyannis and Boston Medical Center. The earliest departure is at 9:30 AM in the morning, and the last departure from Hyannis is at 5:15 PM which arrives into Boston Medical Center at 7:26 PM. All services require a transfer at Essex St @ Atlantic Ave and take an average of 2h 3m. The schedules shown below are for the next available departures.

2h 11m • 1 change

2h 8m • 1 change

1h 53m • 1 change

2h 5m • 1 change
Want to know about travelling from Hyannis to Boston Medical Center? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Boston Medical Center. However, there are services departing from Hyannis station and arriving at Boston Medical Center station via Boston South Station station. The journey, including transfers, takes approximately 2h 3m.
Hyannis to Boston Medical Center bus services, operated by Peter Pan Bus Lines, depart from Hyannis Transportation Center station.
Hyannis to Boston Medical Center bus services, operated by Peter Pan Bus Lines, arrive at Boston South Station.
The distance between Hyannis and Boston Medical Center is 100.1 km. The road distance is 116 km.
Peter Pan Bus Lines operates a bus from Hyannis Transportation Center to Boston South Station every 4 hours. Tickets cost $15–40 and the journey takes 1h 40m.