The average bus between Hyannis and Charlestown takes 2h 29m and the fastest bus takes 2h 7m. There is a bus service every few hours from Hyannis to Charlestown. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hyannis and Charlestown. The earliest departure is at 4:00 AM at night, and the last departure from Hyannis is at 5:30 PM which arrives into Charlestown at 7:48 PM. All services require a transfer at Boston South Station and take an average of 2h 29m. The schedules shown below are for the next available departures.

2h 13m • 1 change

2h 21m • 1 change

2h 12m • 1 change

2h 7m • 1 change

2h 13m • 1 change

2h 21m • 1 change

2h 12m • 1 change

2h 7m • 1 change

2h 13m • 1 change

2h 21m • 1 change

2h 12m • 1 change

2h 7m • 1 change

2h 13m • 1 change

2h 21m • 1 change

2h 12m • 1 change

2h 7m • 1 change
Want to know about travelling from Hyannis to Charlestown? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Charlestown. However, there are services departing from Hyannis station and arriving at Charlestown station via Boston South Station station. The journey, including transfers, takes approximately 2h 29m.
Hyannis to Charlestown bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Charlestown bus services, operated by Plymouth & Brockton, arrive at Boston South Station.
The distance between Hyannis and Charlestown is 103.1 km. The road distance is 116 km.
Peter Pan Bus Lines operates a bus from Hyannis Transportation Center to Boston South Station every 4 hours. Tickets cost $15–40 and the journey takes 1h 40m.