The average bus between Hyannis and Manchester takes 5h 25m and the fastest bus takes 3h 40m. The bus service runs several times per day from Hyannis to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Hyannis and Manchester. The earliest departure is at 4:30 AM at night, and the last departure from Hyannis is at 5:15 PM which arrives into Manchester at 8:10 AM. All services require a transfer at Boston South Station and take an average of 5h 25m. The schedules shown below are for the next available departures.

3h 40m • 1 change

4h 40m • 1 change

3h 50m • 1 change

6h 19m • 1 change

3h 40m • 1 change

4h 40m • 1 change

3h 50m • 1 change

6h 19m • 1 change

4h 40m • 1 change

3h 50m • 1 change

6h 19m • 1 change
Arrives next day

14h 55m • 1 change
Want to know about travelling from Hyannis to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Manchester. However, there are services departing from Hyannis station and arriving at Manchester station via Boston South Station station. The journey, including transfers, takes approximately 5h 25m.
Hyannis to Manchester bus services, operated by Peter Pan Bus Lines, depart from Hyannis Transportation Center station.
Hyannis to Manchester bus services, operated by Peter Pan Bus Lines, arrive at Manchester(Veterans Memorial Park) station.
Book your Hyannis to Manchester bus tickets online with Peter Pan Bus Lines, Jefferson Lines and Greyhound USA.
The distance between Hyannis and Manchester is 177.7 km. The road distance is 199 km.
You can take a bus from Hyannis Transportation Center to Manchester(Veterans Memorial Park) via Boston South Station and Boston in around 3h 50m.