Hyannis to Pennsylvania Buses

Hyannis to Pennsylvania buses

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Trip Overview

The average bus between Hyannis and Pennsylvania takes 10h 11m and the fastest bus takes 8h 30m. The bus service runs several times per day from Hyannis to Pennsylvania. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 11m
Duration: 427 mi
Distance: $91
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Hyannis Transportation Center to Boston South Busesbus
Take the bus from Boston to New York Midtownbus
Take the bus from New York Midtown to Philadelphia Bus Stationbus

10h 10m

$78–120

Hyannis to Pennsylvania bus times

Buses run every 4 hours between Hyannis and Pennsylvania. The earliest departure is at 5:00 AM in the morning, and the last departure from Hyannis is at 9:00 PM which arrives into Pennsylvania at 9:00 AM. All services require a transfer at Boston, South Station and take an average of 10h 11m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

6:00 AM → 2:30 PM
8h 30m • 2 changes
8:00 AM → 6:00 PM
10h • 2 changes
1:00 PM → 9:55 PM
8h 55m • 2 changes
5:30 PM → 3:00 AM
Arrives next day
9h 30m • 2 changes
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Departing Sunday, October 11, 2026

6:00 AM → 2:30 PM
8h 30m • 2 changes
8:00 AM → 6:00 PM
10h • 2 changes
1:00 PM → 9:55 PM
8h 55m • 2 changes
5:30 PM → 3:00 AM
Arrives next day
9h 30m • 2 changes
Show more

Departing Monday, October 12, 2026

6:00 AM → 2:30 PM
8h 30m • 2 changes
8:00 AM → 6:00 PM
10h • 2 changes
1:00 PM → 9:55 PM
8h 55m • 2 changes
5:30 PM → 3:00 AM
Arrives next day
9h 30m • 2 changes
Show more

Departing Tuesday, October 13, 2026

6:00 AM → 2:30 PM
8h 30m • 2 changes
8:00 AM → 7:45 PM
11h 45m • 2 changes
1:00 PM → 9:55 PM
8h 55m • 2 changes
5:30 PM → 3:00 AM
Arrives next day
9h 30m • 2 changes
Show more

Departing Wednesday, October 14, 2026

5:00 AM → 2:30 PM
9h 30m • 2 changes
5:30 PM → 3:00 AM
Arrives next day
9h 30m • 2 changes
9:00 PM → 9:00 AM
Arrives next day
12h • 2 changes

Departing Thursday, October 15, 2026

6:00 AM → 2:30 PM
8h 30m • 2 changes
1:00 PM → 11:00 PM
10h • 2 changes
5:30 PM → 3:00 AM
Arrives next day
9h 30m • 2 changes
6:45 PM → 6:50 AM
Arrives next day
12h 5m • 2 changes
Show more

Departing Friday, October 16, 2026

6:00 AM → 2:30 PM
8h 30m • 2 changes
8:00 AM → 6:00 PM
10h • 2 changes

Frequently asked questions

Want to know about travelling from Hyannis to Pennsylvania? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Hyannis to Pennsylvania buses

Trip Overview

Bus