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Hyannis to Philadelphia buses

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Trip Overview

The average bus between Hyannis and Philadelphia takes 10h 13m and the fastest bus takes 8h 30m. The bus service runs several times per day from Hyannis to Philadelphia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 13m
Duration
427 mi
Distance
$91
Average price
5 times a day
Frequency

Bus via New York

best
  1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
  2. Take the bus from Boston to New York Midtownbus bus
  3. Take the bus from New York Midtown to Philadelphia Bus Stationbus bus
10h 10m
$78–120

Hyannis to Philadelphia bus times

Buses run 5 times a day between Hyannis and Philadelphia. The earliest departure is at 5:00 AM in the morning, and the last departure from Hyannis is at 9:00 PM which arrives into Philadelphia at 9:00 AM. All services require a transfer at Boston, South Station and take an average of 10h 13m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

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    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA12h • 2 changes

Departing Saturday, October 10, 2026

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 30m • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA10h • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 55m • 2 changes

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    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA9h 30m • 2 changes
  • Show more

Departing Sunday, October 11, 2026

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 30m • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA10h • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 55m • 2 changes

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    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA9h 30m • 2 changes
  • Show more

Departing Monday, October 12, 2026

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 30m • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA10h • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 55m • 2 changes

  •  → 

    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA9h 30m • 2 changes
  • Show more

Departing Tuesday, October 13, 2026

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 30m • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA11h 45m • 2 changes

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 55m • 2 changes

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    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA9h 30m • 2 changes
  • Show more

Departing Wednesday, October 14, 2026

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    Plymouth & BrocktonFlixbus USAFlixbus USA9h 30m • 2 changes

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    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA9h 30m • 2 changes

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    Arrives next day

    Plymouth & BrocktonFlixbus USAFlixbus USA12h • 2 changes

Departing Thursday, October 15, 2026

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    Plymouth & BrocktonFlixbus USAFlixbus USA8h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Hyannis to Philadelphia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Hyannis to Philadelphia.ExpandLaunch map view
  • Distance: 426.7 mi
  • Duration: 10h 13m

What companies run services between Hyannis, MA, USA and Philadelphia, PA, USA?

You can take a bus from Hyannis Transportation Center to Philadelphia Bus Station via Boston, South Station, Boston, and New York Midtown in around 10h 10m.

Operators