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Hyannis to Saco buses

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Trip Overview

The average bus between Hyannis and Saco takes 7h 19m and the fastest bus takes 5h 28m. The bus service runs several times per day from Hyannis to Saco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 19m
Duration
202 mi
Distance
$64
Average price
4 times a day
Frequency

Bus, line 60 bus

best
  1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
  2. Take the bus from Boston, MA - South Station to Portland, MEbus bus
  3. Take the bus from St John St to 292 Main Stbus bus 60
6h 33m
$52–86

Hyannis to Saco bus times

Buses run 4 times a day between Hyannis and Saco. The earliest departure is at 6:00 AM in the morning, and the last departure from Hyannis is at 9:00 PM which arrives into Saco at 8:28 AM. All services require a transfer at Boston, South Station and take an average of 7h 19m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

  •  → 

    Arrives next day

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit16h 13m • 3 changes

Departing Saturday, October 10, 2026

  •  → 

    Arrives next day

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit13h 38m • 3 changes

Departing Sunday, October 11, 2026

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    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit7h 10m • 3 changes

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    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit6h 27m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit6h 13m • 3 changes

  •  → 

    Arrives next day

    Plymouth & BrocktonConcord Coach LinesGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit11h 28m • 3 changes

Departing Monday, October 12, 2026

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    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 34m • 3 changes

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    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 44m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 28m • 3 changes

  •  → 

    Plymouth & BrocktonConcord Coach LinesGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 49m • 3 changes
  • Show more

Departing Tuesday, October 13, 2026

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 34m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 44m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 28m • 3 changes

  •  → 

    Plymouth & BrocktonConcord Coach LinesGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 49m • 3 changes
  • Show more

Departing Wednesday, October 14, 2026

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 34m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 44m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 28m • 3 changes

  •  → 

    Plymouth & BrocktonConcord Coach LinesGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 49m • 3 changes
  • Show more

Departing Thursday, October 15, 2026

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 34m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 44m • 3 changes

  •  → 

    Plymouth & BrocktonAmtrak ThruwayGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 28m • 3 changes

  •  → 

    Plymouth & BrocktonConcord Coach LinesGreater Portland Metro BusBiddeford Saco Old Orchard Beach Transit5h 49m • 3 changes

Frequently asked questions

Want to know about travelling from Hyannis to Saco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Hyannis to Saco.ExpandLaunch map view
  • Distance: 201.7 mi
  • Duration: 7h 19m

What companies run services between Hyannis, MA, USA and Saco, ME, USA?

You can take a bus from Hyannis Transportation Center to 292 Main St via Boston, South Station, Boston, MA - South Station, Ptc, Congress + Union Station Plaza, and St John St in around 6h 33m.

Operators