The average bus between Hyannis and Times Square–42nd Street Station takes 6h 55m and the fastest bus takes 6h 20m. There is a bus service every few hours from Hyannis to Times Square–42nd Street Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hyannis and Times Square–42nd Street Station. The earliest departure is at 4:00 AM at night, and the last departure from Hyannis is at 9:00 PM which arrives into Times Square–42nd Street Station at 5:30 AM. All services require a transfer at Boston, South Station and take an average of 6h 55m. The schedules shown below are for the next available departures.

6h 35m • 1 change

6h 40m • 1 change

6h 45m • 1 change

6h 50m • 1 change

7h • 1 change

6h 35m • 1 change

6h 20m • 1 change

6h 45m • 1 change

7h 35m • 1 change

7h • 1 change

6h 20m • 1 change

6h 35m • 1 change

7h 35m • 1 change

7h • 1 change

6h 20m • 1 change

6h 35m • 1 change
Want to know about travelling from Hyannis to Times Square–42nd Street Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Times Square–42nd Street Station. However, there are services departing from Hyannis station and arriving at Times Square–42nd Street Station station via Boston South Buses. The journey, including transfers, takes approximately 6h 55m.
Hyannis to Times Square–42nd Street Station bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Times Square–42nd Street Station bus services, operated by Plymouth & Brockton, arrive at New York Midtown station.
The distance between Hyannis and Times Square–42nd Street Station is 325.4 km. The road distance is 459 km.
You can take a bus from Hyannis Transportation Center to Times Square–42nd Street Station via Boston, South Station, Boston, and New York Midtown in around 7h 20m.