The average bus between Hyatt Regency San Francisco and Santa Cruz takes 4h 50m and the fastest bus takes 2h 32m. The bus service runs several times per day from Hyatt Regency San Francisco to Santa Cruz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Hyatt Regency San Francisco and Santa Cruz. The earliest departure is at 7:45 AM in the morning, and the last departure from Hyatt Regency San Francisco is at 10:35 PM which arrives into Santa Cruz at 7:05 AM. All services require a transfer at San Francisco and take an average of 4h 50m. The schedules shown below are for the next available departures.

2h 39m • 1 change

3h 1m • 1 change
Arrives next day

8h 30m • 1 change

2h 39m • 1 change

3h 1m • 1 change
Arrives next day

10h 20m • 1 change

2h 32m • 1 change

2h 43m • 1 change
Arrives next day

10h 20m • 1 change

2h 32m • 1 change

2h 43m • 1 change
Arrives next day

8h 30m • 1 change

2h 39m • 1 change

3h 1m • 1 change
Arrives next day

8h 30m • 1 change
Want to know about travelling from Hyatt Regency San Francisco to Santa Cruz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyatt Regency San Francisco to Santa Cruz. However, there are services departing from Hyatt Regency San Francisco station and arriving at Santa Cruz station via San Jose. The journey, including transfers, takes approximately 4h 50m.
Hyatt Regency San Francisco to Santa Cruz bus services, operated by Amtrak, depart from San Francisco station.
Hyatt Regency San Francisco to Santa Cruz bus services, operated by Amtrak, arrive at Soquel Ave & Front station.
The distance between Hyatt Regency San Francisco and Santa Cruz is 96.7 km. The road distance is 128 km.
You can take a vehicle from Hyatt Regency San Francisco to Soquel Ave & Front via San Francisco, San Jose, and Diridon Station in around 2h 37m.