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Illinois to Mayo Clinic buses

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Trip Overview

The average bus between Illinois and Mayo Clinic takes 11h 10m and the fastest bus takes 8h 10m. The bus runs, on average, 2 times per week from Illinois to Mayo Clinic. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 10m
Duration
353 mi
Distance
$117
Average price
Twice a week
Frequency

Illinois to Mayo Clinic bus times

Buses run twice a week between Illinois and Mayo Clinic. The service departs Illinois at 11:30 PM at night, which arrives into Mayo Clinic at 14:40:00. All services require a transfer at 250 N. Lake St - Madison UW Campus and take an average of 11h 10m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    Rockland CoachesJefferson Lines14h 10m • 1 change

Frequently asked questions

Want to know about travelling from Illinois to Mayo Clinic? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Illinois to Mayo Clinic.ExpandLaunch map view
  • Distance: 353.1 mi
  • Duration: 11h 10m

What companies run services between Illinois, USA and Mayo Clinic, MN, USA?

You can take a bus from W Jackson Blvd, after S Clinton St to Mayo Clinic via 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 9h 8m.

Operators